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Could a tailored lifestyle program ward off dementia?

NCT ID NCT07698431

Prevention Sponsor: Barcelonabeta Brain Research Center, Pasqual Maragall Foundation Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 13, 2026 · Last updated Sep 17, 2026 · Updated 3 times

Summary

This study tests a brain health service designed to assess and reduce dementia risk in people aged 55 to 85 who have subjective cognitive decline (memory concerns without objective impairment). Participants are randomly assigned to either a personalized 6-month program—combining diet, exercise, sleep, social engagement, and cognitive training—or general prevention advice. The goal is to see if such a service is feasible and can lead to healthier lifestyle changes that may lower dementia risk.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Multimodal Lifestyle Intervention (personalized diet, physical activity, sleep, social engagement, cognitive stimulation)
What this could lead to
If successful, this approach could provide a scalable, personalized way to reduce dementia risk in people with early memory concerns.
What could go wrong
This is a small feasibility study, so results may not apply broadly. The intervention requires significant participant commitment, and long-term benefits are not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2026

Expected to finish

Aug 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

55 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants aged 55 to 85 with subjective cognitive complaints and normal screening test performance at the hospital. * Participants must have a minimal educational level for a neuropsychological assessment and a minimal digital literacy for the usage of smartphones, computers and Internet. Exclusion Criteria: * Objective cognitive impairment. * Clinically relevant neurological disorders. * Major psychiatric disorders. * History of drug/alcohol abuse. * Unstable medical conditions that could fully explain cognitive complaints, as determined by the investigator.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease subjective cognitive decline dementia prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Subjective cognitive decline (SCD)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Fundació Pasqual Maragall

    RECRUITING

    Barcelona, Catalonia, 08005, Spain

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