Can brain scans reveal the secrets of a healthy mind?
NCT ID NCT06731452
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This pilot study is looking for new ways to measure brain health using non-invasive techniques like EEG and TMS. Researchers will test 63 healthy adults who are already part of a larger brain health study. The goal is to see if these brain imaging tools can provide useful markers of how well the brain is working.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Strategic Memory Advanced Reasoning Training (SMART) - a behavioral training program
- What this could lead to
- If successful, this study could help identify simple, non-invasive brain tests to measure and track brain health in healthy people.
- What could go wrong
- This is a small pilot study with only 63 participants, so results may not apply to everyone. It is exploratory and not designed to prove any treatment works.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 63 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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22 to 100 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Must be an active brain imaging participant in The BrainHealth Project (NCT04869111) * Minimum age of 22 * Fluent in English * Able to read \& hear information over a computer * Must pass an MRI safety screener to assess the presence of contraindicators for MRI compatibility (i.e., non-removable metal within/on the body, claustrophobia, pregnancy, non-correctable vision problems, head trauma, and CNS disease)or other standard requirements as determined by the Imaging Center. * Must pass a modified TMS Adult Safety Screen * Meet all criteria for study as determined by the study physician Exclusion Criteria: * A diagnosis of a neurodegenerative disease * A history of stroke, concussion, or brain injury that currently hinders them from functioning at their prior level * A diagnosis of autism spectrum disorder that currently hinders them from functioning independently. * Metallic brain implants or fragments (like a shunt, pacemaker, clips, coils, bullet fragments, cochlear implants) * Magnetically activated implants or electronically implanted devices * Medication pumps * Personal or family history of epilepsy, seizure(s), seizure disorder. * History of, or risk factors for syncope (fainting) * Report significant cognitive challenges * Report untreated health issues (like substance abuse, hypertension, hypo- or hyper-thyroidism) * Have claustrophobia
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Center for BrainHealth at The University of Texas at Dallas
RECRUITINGDallas, Texas, 75235, United States
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