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Cardiac arrest Survivors' brains under the scanner: new study reveals hidden effects

NCT ID NCT03579498

Knowledge-focused Sponsor: Uppsala University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how a cardiac arrest affects brain function, including memory, thinking, and emotions. Researchers will follow 48 survivors for one year, using cognitive tests and brain scans (fMRI) to track changes. Their results will be compared to a healthy control group to understand the long-term impact.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors understand how cardiac arrest affects thinking and emotions, and guide better support for survivors.
What could go wrong
This is an observational study with only 48 participants, so results may not apply to everyone. It does not test any treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

48 people

The number who actually took part.

Started

Feb 2018

Finished

Nov 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of 30 cardiac arrest patients and 30 matched (regarding age, gender and educational level), healthy controls.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients who have suffered a cardiac arrest of cardiac cause who were admitted to hospital after the event. * Age 18-70 * Consents to participating in the study Exclusion Criteria: * Terminal disease with expected survival \<1 year, moribund patient with \>1 treatment limitations. * A history of brain injury or brain disease that affects cognitive function, such as dementia * Severe psychiatric disorder, for example psychotic disorders or severe alcohol use disorder * Insufficient knowledge of the spoken language to understand instructions and answer questionnaires (oral or written) * Deceased within 1 month.

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Conditions

The condition(s) this trial relates to.

anxiety disorder cardiac arrest Cognitive Dysfunction Depression post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiac arrest Cognitive function

Contacts and locations

Locations

  • Haukeland University Hospital

    Bergen, 5021, Norway

  • Uppsala University Hospital

    Uppsala, 75185, Sweden

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