Scientists probe Brain's response to mild oxygen drops
NCT ID NCT07516028
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how breathing air with slightly less oxygen (moderate hypoxia) changes brain activity and nerve signals in 36 healthy adults aged 18 to 65. Researchers will use EEG and fNIRS to measure brain waves and blood flow, and TMS to test nerve responses. The goal is to understand the brain's reaction to low oxygen, which may help develop new therapies for conditions like high blood pressure or diabetes.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 36 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male or female aged 18 to 65 years * Healthy right- or left-handed individuals with no self-reported neurological disorders or history of neurological conditions (e.g., epilepsy, stroke, brain or spinal surgery, or neurological diseases affecting motor or sensory function such as multiple sclerosis, or neurodegenerative diseases such as Parkinson's or Alzheimer's) * Individuals who have provided informed consent and have sufficient proficiency in French * Participants affiliated with, or beneficiaries of, a social security scheme Exclusion Criteria: * Body mass index (BMI) greater than 30 kg/m² * Diagnosed and untreated obstructive sleep apnoea syndrome * Inability to provide informed consent * History of cardiac (e.g., ischaemic heart disease, heart failure) and/or respiratory disorders (e.g., COPD, chronic respiratory insufficiency, persistent or uncontrolled asthma) * Current smokers * Contraindications to TMS (e.g., uncontrolled epilepsy, intracranial metallic foreign body, hearing aid or cochlear implant, implanted stimulator or pump, scalp lesions, elevated intracranial pressure, cerebrospinal fluid shunt) * Use of psychotropic medication * Individuals under legal guardianship or curatorship * Pregnant or breastfeeding women * Participants who have flown by air or travelled to terrestrial altitudes above 1500 metres within the seven days prior to inclusion
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Eurasport
Loos, Hauts-de-France, 59120, France