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Brain scans reveal hidden link between masking and anorexia in autism

NCT ID NCT07098156

Knowledge-focused Sponsor: University of Aberdeen Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 04, 2026 · Updated 2 times

Summary

This study looks at how autistic people who also have anorexia nervosa differ in brain structure and behavior from autistic people without anorexia. Researchers want to understand if 'masking' (acting non-autistic to fit in) is linked to eating disorder symptoms and brain changes. Participants will fill out questionnaires and get an MRI scan. This is an observational study, not a treatment trial.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

29 people

The number who actually took part.

Started

Jun 2025

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The population for this study consists of Autistic individuals who both present or do not present with acute anorexia nervosa. Study population will be recruited from Scotland, primarily the NHS Grampian region.

Ages

25 to 45 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Healthy Autistic Individuals (Autistic Controls) must: * Be aged 25-45 years * Be Autistic (clinically diagnosed and/or have an Autism Quotient (AQ-10) score of ≥6) * Be able to provide informed consent for the study * Be able to read, understand and respond to questionnaires in English * Have no history of an eating disorder * Willing to have an MRI scan in Aberdeen Autistic Individuals with anorexia nervosa must: * Be aged 25-45 years * Be Autistic (clinically diagnosed and/or have an AQ-10 score of ≥6) * Be able to provide informed consent to the study * Be able to read, understand and respond to questionnaires in English * Have a diagnosis of anorexia nervosa or a body mass index of \<18.5 * Willing to have an MRI scan in Aberdeen Exclusion Criteria: Individuals are not eligible for the study if they: * Are aged \<25 or \>45 years * Are not Autistic or not clinically diagnosed as Autistic and have an AQ-10 score of \<6 * Are diagnosed with an eating disorder other than anorexia nervosa * Have a history of brain injury (e.g., stroke) * Be unable to provide informed consent for the study * Have contraindications to MRI scanning, such has implantable cardiac devices * Are unable to read, understand and respond to questionnaires in English * As participants will need to consent to the study and complete questionnaires by themselves, individuals with intellectual disability will be excluded from this study

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Conditions

The condition(s) this trial relates to.

anorexia nervosa autism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anorexia nervosa Autism

Contacts and locations

Locations

  • Lilian Sutton Building

    Aberdeen, Aberdeen City, AB25 2ZD, United Kingdom

  • NHS Grampian Eating Disorder Services

    Aberdeen, Aberdeen City, AB25 2ZD, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.