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Sound waves open brain barrier to deliver drug in Parkinson's trial

NCT ID NCT04370665

First seen Jan 26, 2026 · Last updated May 25, 2026 · Updated 17 times

Summary

This small pilot study tested a new way to get the drug Cerezyme into the brains of 4 people with Parkinson's disease. Doctors used MRI-guided focused ultrasound to temporarily open the blood-brain barrier, allowing the drug to reach a targeted area. The main goal was to see if the barrier could be safely opened and the drug delivered, not to treat symptoms.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Sunnybrook Health Sciences Centre

    Toronto, Ontario, M4N 3M5, Canada

Conditions

Explore the condition pages connected to this study.