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Brain scans could reveal the best depression drug for you

NCT ID NCT05892744

First seen May 07, 2026 · Last updated May 17, 2026 · Updated 3 times

Summary

This study aims to find brain biomarkers that can predict how individuals with major depression will respond to the antidepressant sertraline (Zoloft). Researchers will use fMRI and EEG to measure brain activity and connections in 50 adults with chronic or recurrent depression. Participants will take sertraline for 8 weeks, and their symptom changes will be compared to their brain scans to identify predictive patterns.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Health Discovery Building (HDB), 1601 Trinity St., Bldg B., Z0600

    RECRUITING

    Austin, Texas, 78712, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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