Brain zap study reveals emotional wiring in Parkinson's
NCT ID NCT01537224
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how the brain's emotional centers work in people with Parkinson's disease who had just received a deep brain stimulator implant. Researchers measured brain activity while patients listened to sounds or saw images with emotional meaning. The goal was to better understand how deep brain stimulation affects mood and motivation, not to treat the disease.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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22 people
The number who actually took part.
- Started
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Sep 2011
- Finished
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Oct 2016
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient with Parkinson's disease selected for deep brain stimulation (DBS) of the subthalamic nucleus (STN) in accordance with the criteria established by Welter and colleagues (Welter et al., 2002); * Aged 18 years or above; * Written informed consent from the patient. Exclusion Criteria: * Patient under a legal incapacity or with limited legal capacity; * Patient who has perioperative complications or postoperative confusion; * Patient displaying cognitive disturbances involving the early stages of speech processing (on the basis of an audiogram systematically conducted prior to surgery) ; * Patient displaying cognitive disturbances involving the early stages of face processing (on the basis of the Benton Facial Recognition Test (Benton, Hamsher, Varney, \& Spreen, 1983) systematically administered prior to surgery); * Patient incapable of understanding the information given about the study, performing the tasks or providing informed consent.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU Rennes
Rennes, 35000, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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