New study tracks tumor DNA in brain cancer patients during experimental treatment
NCT ID NCT06610682
First seen Dec 29, 2025 · Last updated May 20, 2026 · Updated 19 times
Summary
This early-phase trial is for people with a specific type of brain tumor (glioma) that has a BRAF-V600E mutation and has not responded to prior treatments. The study aims to see if tumor DNA can be detected in blood and spinal fluid samples before and during treatment with the drugs plixorafenib alone or combined with retifanlimab. About 24 participants will be enrolled to help researchers understand how these DNA levels change with treatment response.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Johns Hopkins
RECRUITINGBaltimore, Maryland, 21231, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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