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Promising combo tackles relapsed lymphoma in small trial

NCT ID NCT02433795

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This phase 2 study tested a combination of two drugs, bendamustine and rituximab, in 27 people with relapsed or progressive marginal zone B-cell lymphoma. The goal was to see how well the treatment shrank or controlled the cancer. Participants had already tried at least one prior therapy. The study is complete, and results may help guide future treatment for this type of lymphoma.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Chonbuk National University Hospital

    Jeonju, Jeollabuk-do, 54907, South Korea

  • Chungnam National University

    Daejeon, South Korea

  • Gachon University Gil Medical Center

    Incheon, South Korea

  • Gyeongsang National University Hospital

    Jinju, South Korea

  • Hallym University Medical Center

    Anyang-si, South Korea

  • Inje Universit

    Seoul, South Korea

  • Korea Cancer Center Hospital

    Seoul, South Korea

  • Seoul National University Boramae Hospital

    Seoul, South Korea

  • Seoul National University Bundang Hospital

    Seongnam, South Korea

  • Seoul National University Hospital

    Seoul, South Korea

  • The Catholic University of Korea

    Seoul, South Korea

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bendamustine plus rituximab

What this could lead to

If successful, this combination could offer a treatment option for people with relapsed marginal zone lymphoma, helping to shrink or control the cancer.

What could go wrong

This is a small, phase 2 study with only 27 participants, so results may not apply to everyone. The treatment also has side effects like low blood counts and infection risk.

Conditions

The condition(s) this trial relates to.

Lymphoma, B-Cell, Marginal Zone marginal zone lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.