New hope for tough myeloma: early trial of BP2202 begins
NCT ID NCT07667868
First seen Jun 27, 2026 · Last updated Aug 21, 2026 · Updated 5 times
Summary
This early-stage trial is testing a new drug called BP2202 in 24 people with multiple myeloma that has come back or no longer responds to standard treatments. The main goal is to see if BP2202 is safe and to find the best dose. Researchers will also watch for any signs that the drug is shrinking the cancer.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- BP2202 (a biological drug given by IV infusion)
- What this could lead to
- If this early trial shows BP2202 is safe and works, it could point toward a new treatment option for people with multiple myeloma that has come back or stopped responding to other therapies.
- What could go wrong
- This is a very early Phase 1 trial with only 24 participants, so it is mainly checking safety, not effectiveness. The drug may not work well enough to move forward, and side effects could be serious.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
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About 18 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosis of Multiple Myeloma with relapsed or refractory disease. * Eastern Cooperative Oncology Group (ECOG) Performance Status score of 0 or 1 * Adequate organ function. * Have measurable disease Exclusion Criteria: * Known active central nervous system (CNS) involvement or exhibits clinical signs of meningeal involvement of Multiple Myeloma. * Known second malignancy that is progressing or requires active treatment or may interfere with study endpoints.
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Get notified about this study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Engineered immune cells target CS1 to fight stubborn myeloma
- Can a Pre-Dose prevent a dangerous reaction in multiple myeloma treatment?
- New drug combo aims to tackle Hard-to-Treat myeloma
- New hope for myeloma patients: epunamin combo under study
- New combo therapy aims to tackle Hard-to-Treat myeloma
- New drug duo aims to tackle Hard-to-Treat myeloma