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A simple breathing trick may calm colonoscopy nerves — a trial puts it to the test

NCT ID NCT07728890

Symptom relief Sponsor: Tarsus University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 27, 2026 · Last updated Aug 05, 2026 · Updated 4 times

Summary

This trial tests whether box breathing — a technique of inhaling, holding, exhaling, and holding for 4 seconds each — can reduce anxiety, pain, and improve lung function in people undergoing colonoscopy. Half of the 68 participants will practice the breathing exercise before the procedure, while the other half receives standard care. Researchers will measure anxiety, pain, and breathing tests before and after the procedure to see if this simple technique makes a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
box breathing exercises (4-4-4-4 breathing technique)
What this could lead to
If it works, this simple breathing exercise could offer a drug-free way to reduce anxiety and pain during colonoscopy.
What could go wrong
This is a small, early-stage trial. The technique may not significantly reduce anxiety or pain, and results may not apply to other procedures.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 68 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * are 18 years of age or older; * are scheduled to undergo colonoscopy; * are conscious, oriented, and able to cooperate; * provide written informed consent to participate in the study; * are able to speak and understand Turkish; and * have no physical disabilities that would interfere with study participation. Exclusion Criteria: * decline to participate or choose to withdraw from the study; * have a chronic respiratory disease; * have chest pain; * have nasal abnormalities (e.g., nasal septal deviation) or adenoid hypertrophy -that may affect ventilation; * have previously practiced box breathing exercises; or * have chronic pain.

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Conditions

The condition(s) this trial relates to.

anxiety disorder Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colonoscopy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

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