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Could a plastic bottle help people with Parkinson's breathe easier and stay steady?

NCT ID NCT07680725

Disease control Sponsor: Marmara University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study investigates whether a homemade bottle-based breathing device can strengthen the muscles used for exhaling and improve balance in people with Parkinson's disease. Parkinson's often weakens respiratory muscles, leading to breathing and coughing problems. The trial will measure changes in muscle thickness, breathing strength, and balance in 42 participants who use the device regularly. If successful, this low-cost approach could offer a simple way to manage two common Parkinson's challenges.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bottle positive expiratory pressure (PEP) device
What this could lead to
If effective, this low-cost breathing exercise could become a simple home therapy to help people with Parkinson's breathe better and reduce fall risk.
What could go wrong
This is a small, early-stage study with only 42 participants. The exercise may not produce meaningful improvements, and results may not apply to all Parkinson's patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 42 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2025

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients aged 18-75 with a diagnosis of Parkinson's disease who are ambulatory

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with a confirmed Parkinson's diagnosis who are being monitored * Those aged 18-75 * Patients who are ambulatory Exclusion Criteria: * Patients with acquired primary motor neuron disease (ischemic/hemorrhagic stroke, intracranial mass) and additional neurological diagnoses * Patients with hearing and cognitive impairments that prevent them from understanding or performing the exercise program * Presence of concomitant acute or chronic lung disease * History of thoracic or abdominal surgery * Severe heart disease * Active cancer * Mini-Mental State Examination (MMSE) score ≤ 24 * Active smoking

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Parkinson disease (PD)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Marmara University Medical Faculty

    RECRUITING

    Istanbul, Maltepe, 34854, Turkey (Türkiye)

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