Botox or splints? study tests best way to stop teeth grinding in denture wearers
NCT ID NCT07361900
First seen Jan 27, 2026 · Last updated Jun 23, 2026 · Updated 20 times
Summary
This study tested three approaches for sleep bruxism (teeth grinding) in 48 people with implant-supported dentures: Botox injections into the jaw muscles, a custom mouth splint, or simply removing the denture at night. Researchers measured muscle activity and denture retention over 12 months. The goal was to see which method best reduces grinding and keeps dentures secure.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Delta University for Science and Technology
Gamasa, Egypt
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Botulinum toxin type A (Botox) injection
What this could lead to
If Botox works better than splints or no treatment, it could offer a simple, effective way to reduce jaw muscle activity and improve denture retention for people with bruxism.
What could go wrong
This is a small, early-phase study with only 48 participants. Results may not apply to everyone, and Botox injections carry risks like temporary muscle weakness or pain at the injection site.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.