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BOTOX users report high satisfaction with natural look in new study

NCT ID NCT06218251

Symptom relief Sponsor: AbbVie Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested how satisfied adults were with the natural look of their face after BOTOX injections for frown lines, crow's feet, and forehead wrinkles. About 100 participants received BOTOX at the start and filled out questionnaires about their satisfaction and psychological well-being. The goal was to see if people felt the results looked natural.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
BOTOX (botulinum toxin type A)
What this could lead to
If successful, this study could confirm that BOTOX provides a natural-looking result that patients are happy with.
What could go wrong
This is a small, completed Phase 4 study with no comparison group, so results may not apply to everyone. Side effects like bruising or temporary muscle weakness are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

100 people

The number who actually took part.

Started

Feb 2024

Finished

Dec 2024

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Moderate to severe Glabellar Lines, Lateral Canthal Lines, and Forehead Lines. * Sufficient visual acuity without the use of eyeglasses (contact lens use acceptable) to accurately assess their facial wrinkles. Exclusion Criteria: * Presence or history of any medical condition that may place the participant at increased risk to BOTOX Cosmetic or interfere with the study evaluation. * Presence of tattoos, jewelry, or clothing which obscures or interferes with the target area of interest and cannot be removed. * History of known immunization or hypersensitivity to any botulinum toxin serotype.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Upper facial lines

Contacts and locations

Locations

  • Bertucci MedSpa Inc. /ID# 249757

    Woodbridge, Ontario, L4L 8E2, Canada

  • Integrated Aesthetics - Spring /ID# 257738

    Spring, Texas, 77388, United States

  • Kavali Plastic Surgery and Skin Renewal Center /ID# 248472

    Atlanta, Georgia, 30328, United States

  • Pacific Clinical Innovations /ID# 248467

    Vista, California, 92083-6030, United States

  • Project Skin MD - Ottawa /ID# 249718

    Ottawa, Ontario, K1K 2Z7, Canada

  • Skin Matters Medical Aesthetic Centre /ID# 249539

    Vancouver, British Columbia, V6M 4J2, Canada

  • Skin Wellness Dermatology - Homewood /ID# 248469

    Birmingham, Alabama, 35209-8314, United States

  • SkinDC /ID# 248470

    Arlington, Virginia, 22209, United States

  • Tennessee Clinical Research Center /ID# 259161

    Nashville, Tennessee, 37215-2885, United States

  • The Research Center at The Maas Clinic /ID# 256633

    San Francisco, California, 94115-1809, United States