Jaw-dropping results: BOTOX shrinks bulky jaw muscles in new study
NCT ID NCT06387394
First seen Jan 04, 2026 · Last updated May 24, 2026 · Updated 18 times
Summary
This study tested whether BOTOX injections can safely reduce the size of the masseter muscle, the chewing muscle that can make the lower face look wide. About 200 adults with noticeable jaw muscle bulk received either BOTOX or a placebo. The results showed that BOTOX improved the appearance of the jawline, as rated by both doctors and participants, with few side effects.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Austin Institute for Clinical Research - Pflugerville /ID# 248217
Pflugerville, Texas, 78660, United States
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Ava T. Shamban MD - Santa Monica. /ID# 248886
Santa Monica, California, 90404-2208, United States
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Bellaire Dermatology Associates /ID# 248221
Bellaire, Texas, 77401, United States
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Centricity Research Dublin Multispecialty /ID# 248484
Dublin, Ohio, 43016, United States
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Clarkston Dermatology /ID# 248888
Clarkston, Michigan, 48346, United States
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Coleman Center For Cosmetic Dermatologic Surgery /ID# 249827
Metairie, Louisiana, 70006, United States
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Cosmetic Laser Dermatology /ID# 248215
San Diego, California, 92121-2119, United States
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DMR Research PLLC /ID# 248485
Westport, Connecticut, 06880, United States
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Dallas Plastic Surgery Institute /ID# 248220
Dallas, Texas, 75231, United States
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Delricht Research /ID# 249825
New Orleans, Louisiana, 70115, United States
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Edwin F. Williams III, MD FACS of LATHAM P.C. D/B/A THE REJUVA CENTER /ID# 248887
Latham, New York, 12110, United States
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Mayo Clinic Arizona /ID# 248883
Phoenix, Arizona, 85054, United States
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Skin Care and Laser Physicians of Beverly Hills /ID# 248223
Los Angeles, California, 90069, United States
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Skin Laser and Surgery Specialists of NY and NJ /ID# 251501
Hackensack, New Jersey, 07601-1997, United States
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Skin and Cancer Associates, LLP /ID# 248209
Miami, Florida, 33137-3254, United States
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SkinDC /ID# 248885
Arlington, Virginia, 22209, United States
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Susan H. Weinkle MD /ID# 252063
Bradenton, Florida, 34209-5642, United States
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Tennessee Clinical Research Center /ID# 248486
Nashville, Tennessee, 37215-2885, United States
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Total Skin and Beauty Dermatology Center /ID# 248218
Birmingham, Alabama, 35205, United States
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Wilmington Dermatology Center /ID# 250651
Wilmington, North Carolina, 28403, United States
Conditions
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