Botanical sleep aid challenges melatonin in new study
NCT ID NCT06894108
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 38 times
Summary
This study tested a special blend of plant extracts against melatonin to see which improves sleep quality more. 89 healthy women aged 35-55 with poor sleep took either the botanical supplement or melatonin each night. The goal was to find a natural alternative that works better than the popular sleep hormone.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Nutraceuticals Research Institute
Huntsville, Alabama, 35801, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Proprietary blend of botanical extracts
What this could lead to
If it works, this could offer a natural, non-hormonal sleep aid for women with poor sleep quality.
What could go wrong
This is a small, completed trial with only 89 participants, and the results may not apply to everyone. The botanical blend is proprietary, so its exact ingredients are unknown, and it may not be more effective than melatonin.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.