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New hope for myeloma patients: drug combo shows promise without transplant

NCT ID NCT05272826

First seen Oct 31, 2025 · Last updated May 22, 2026 · Updated 27 times

Summary

This study tests a combination of four drugs (iberdomide, bortezomib, dexamethasone, and isatuximab) for people newly diagnosed with multiple myeloma who cannot have a stem cell transplant. The goal is to see if this treatment can achieve a very deep response (stringent complete response) after four cycles. About 75 participants aged 65 and older will take part. The treatment is adjusted based on how well each person responds.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cross Cancer Institute

    RECRUITING

    Edmonton, Alberta, T6G 1Z2, Canada

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hôpital Maisonneuve-Rosemont

    RECRUITING

    Montreal, Quebec, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • London Health Sciences Centre

    RECRUITING

    London, Ontario, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • McGill University Health Centre

    RECRUITING

    Montreal, Quebec, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • NL Health Services

    RECRUITING

    St. John's, Newfoundland and Labrador, A1B 3V6, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Princess Margaret Hospital

    RECRUITING

    Toronto, Ontario, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • QEII Health Science Centre

    RECRUITING

    Halifax, Nova Scotia, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.