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Scientists probe Athletes' bones to unlock Exercise's hidden effects

NCT ID NCT03386981

Knowledge-focused Sponsor: I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at how different kinds of physical activity change bone metabolism in 200 healthy professional athletes. Researchers will test blood and saliva for markers of bone turnover, hormones, and other substances. The goal is to understand why different sports affect bones differently, which could inform future health recommendations.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help explain how different exercises influence bone health, potentially guiding future training or treatments for bone diseases.
What could go wrong
This is an observational study with no direct treatment, so it won't produce a new therapy. Results may not apply to non-athletes or non-Caucasians.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2016

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

A total of 200 subjects will be recruited. They will be recruited among professional athletes and technical staff of the cooperating teams

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * \>/= 18 yo * healthy status * caucasians Exclusion Criteria: * \< 18 yo * pregnancy status * ongoing or previous (\<5 years) neoplasia * acute or chronic inflammatory pathologies * primary metabolic diseases of bone * recent bone fractures (\< 6 months) * chronic drugs * recent drugs administration (\< 2 months) for non steroidal anti-inflammatory drugs (NSAIDs) and steroids * anxious-depressive conditions * inability to understand the information given by the recruiting physician

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Conditions

The condition(s) this trial relates to.

Bone Diseases, Metabolic metabolic bone disorder Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bone disease, metabolic Physical activity

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Istituto Ortopedico Galeazzi

    RECRUITING

    Milan, 20161, Italy

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