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Jaw bone graft showdown: which material works best for dental implants?

NCT ID NCT07608744

Disease control Sponsor: Ege University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested two types of bone graft materials—alloplastic (man-made) and xenograft (from animals)—to rebuild jaw bone in 20 people who needed dental implants. Each person received both materials in different sides of their jaw so the results could be directly compared. The researchers measured bone gain, pain, swelling, and healing over 6 months to see which material worked better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bone graft materials (alloplastic and xenograft)
What this could lead to
If successful, this could help dentists choose the best bone graft material for patients needing dental implants after jaw bone loss.
What could go wrong
This is a small, early study with only 20 participants. Results may not apply to everyone, and long-term success of the grafts is not yet known.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

Oct 2019

Finished

Oct 2020

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Bilateral mandibular posterior edentulism with indication for implant-supported rehabilitation * Sufficient vertical bone height but insufficient horizontal bone width for implant placement * No infection at surgical site * Non-smoker * No head-and-neck radiotherapy within 2 years * No uncontrolled systemic disease (controlled systemic conditions with INR \<1.2 acceptable) * Signed informed consent Exclusion Criteria: * No indication for implant-supported prosthesis * Smoker * Active infection at surgical site * Head-and-neck radiotherapy within 2 years * Uncontrolled systemic disease * Allergy to study materials * Pregnancy * Age under 18 * Medications interfering with surgical procedures * History of mandibular fracture * Contraindication to surgery determined by consultation * Psychiatric disorder or inability to communication

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Conditions

The condition(s) this trial relates to.

Alveolar Bone Loss Jaw, Edentulous periodontal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alveolar bone loss Edentulous jaw

Contacts and locations

Locations

  • Ege University Faculty of Dentistry

    Izmir, Bornova, 35040, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.