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New drug shows promise in lowering high platelet counts

NCT ID NCT04254978

First seen May 06, 2026 · Last updated May 19, 2026 · Updated 4 times

Summary

This study tested an experimental pill called Bomedemstat in 73 people with essential thrombocythemia, a blood disorder causing too many platelets. Participants had already tried at least one standard treatment without success. The main goals were to check safety and see if the drug could safely lower platelet counts to a normal level.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CRIMM; Centro Ricerca e Innovazione delle Malattia Mieloproliferative, Azienda ospedaliera Universitaria Careggi

    Florence, 50139, Italy

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Department of Hematology and Stem Cell Transplantation, West German Cancer Center (WTZ)

    Essen, 45147, Germany

  • Guys and St Thomas Hospital

    London, SE1 9RT, United Kingdom

  • Local Institution

    Jacksonville, Florida, 32209, United States

  • Local Institution

    Ann Arbor, Michigan, 48109, United States

  • Local Institution

    New York, New York, 10021, United States

  • Local Institution

    Durham, North Carolina, 27710, United States

  • Local Institution

    Pittsburgh, Pennsylvania, 15232, United States

  • Local Institution

    Seattle, Washington, 98109, United States

  • Local Institution

    Herston, Brisbane, Australia

  • Local Institution

    Camperdown, New South Wales, Australia

  • Local Institution

    St Leonards, New South Wales, 2065, Australia

  • Local Institution

    Southport, Queensland, Australia

  • Local Institution

    Clayton, Victoria, 3168, Australia

  • Local Institution

    Jena, Germany

  • Local Institution

    Hong Kong, Hong Kong

  • Local Institution

    Alessandria, Italy

  • Local Institution

    Bologna, Italy

  • Local Institution

    Varese, Italy

  • Local Institution

    Auckland, New Zealand

  • Local Institution

    London, NW1, United Kingdom

  • Local Institution

    London, W12, United Kingdom

  • Local Institution

    Oxford, United Kingdom

  • Middlemore Hospital

    Auckland, New Zealand

  • Royal Adelaide Hospital

    Adelaide, South Australia, 5000, Australia

Conditions

Explore the condition pages connected to this study.