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ER study: does how you give water pills matter for heart failure?

NCT ID NCT07464249

Disease control Sponsor: Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested two methods of giving the diuretic furosemide (a water pill) to 50 people with sudden heart failure in the emergency department. Half received the drug as a single injection (bolus), the other half as a slow drip (continuous infusion). Researchers measured urine output after 2 and 4 hours to see which method works better and faster. The goal is to help ER doctors choose the best approach for treating fluid buildup in heart failure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Furosemide (a diuretic, also known as water pill)
What this could lead to
If one method works better, it could help doctors choose the best way to give diuretics for acute heart failure in the ER, potentially improving urine output and patient outcomes.
What could go wrong
This is a small, single-center study with only 50 patients. Results may not apply to all heart failure patients, especially those with kidney disease. The study only looks at short-term effects (2-4 hours), not long-term outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

50 people

The number who actually took part.

Started

Apr 2024

Finished

Sep 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years * Established diagnosis of heart failure * Presentation with acute decompensation meeting AHA/ACC Stage C-D criteria * New York Heart Association (NYHA) Class III-IV functional status at admission Exclusion Criteria: * Known chronic kidney disease * Hemodynamic instability at presentation * Development of advanced airway requirement during follow-up * Requirement for emergent dialysis

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Conditions

The condition(s) this trial relates to.

congestive heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute decompensated heart failure (ADHF)

Contacts and locations

Locations

  • Sultan 2. Abdulhamid Han Research and Training Hospital

    Istanbul, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.