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New cancer drug BNT314 enters first human safety trial

NCT ID NCT06150183

First seen Oct 31, 2025 · Last updated May 22, 2026 · Updated 27 times

Summary

This study is the first to test BNT314 in humans. It aims to see if the drug is safe when given alone to people with advanced solid tumors that have not responded to other treatments. About 41 participants will receive different doses to find the highest dose that is still safe and tolerable.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHU de Liège

    Liège, 4000, Belgium

  • Carolina BioOncology Institute, LLC

    Huntersville, North Carolina, 28078, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Clinica Universidad de Navarra

    Pamplona, 31008, Spain

  • GZA Ziekenhuizen

    Antwerp, 2018, Belgium

  • Hospital Fund. Jiménez Dia

    Madrid, 28040, Spain

  • Hospital HM Univ. Sanchinarro, Ensayos START

    Madrid, 28050, Spain

  • Hospital Quironsalud Barcelona (NEXT Barcelona)

    Barcelona, 08023, Spain

  • National Cancer Center Hospital East

    Kashiwanoha, 277-8577, Japan

  • Northern Centre for Cancer Care

    Newcastle, NE7 7DN, United Kingdom

  • Rigshospitalet

    Copenhagen, DK-2100, Denmark

  • Royal Marsden Hospital - London

    London, SW36JJ, United Kingdom

  • START Midwest

    Grand Rapids, Michigan, 49546, United States

  • The Christie Hospital

    Manchester, M20 4BX, United Kingdom

Conditions

Explore the condition pages connected to this study.