Syringe vs. pressure bag: which saves more blood in C-Section emergencies?
NCT ID NCT07466719
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two methods of giving blood transfusions to women who have heavy bleeding during a C-section: manual syringing (using a 20 mL syringe) and a pneumatic pressure bag (inflated to 300 mmHg). The goal is to see which method is safer and faster at stabilizing vital signs and which causes less damage to red blood cells. Fifty women aged 18-45 will be randomly assigned to one of the two methods and closely monitored.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could identify a safer and faster way to give blood transfusions during emergency C-sections, especially in hospitals with limited resources.
- What could go wrong
- This is a small, early-stage trial with only 50 participants, so results may not apply to all patients or settings. Both methods are already used in practice, so no major breakthrough is expected.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Apr 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Women aged 18-45 years undergoing cesarean section * Diagnosed major obstetric hemorrhage (blood loss ≥1000 mL or hemodynamic instability requiring transfusion) * Written informed consent for participation Exclusion Criteria: * Pre-existing hemolytic conditions (e.g., sickle cell disease, thalassemia) * Known hypersensitivity to blood products * Severe baseline coagulopathy (defined as INR \> 2.0 or Platelet count \< 50,000/mm³) or established disseminated intravascular coagulation (DIC) prior to randomization * Refusal to receive blood transfusion
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Aswan University Hospital
RECRUITINGAswān, Egypt