Blood test holds promise for colorectal cancer screening
NCT ID NCT05520840
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether proteins in the blood can help screen for colorectal cancer. Researchers tested blood samples from 350 people aged 50 and older who were already scheduled for a colonoscopy. The goal was to see if certain protein markers could reliably detect advanced growths or cancer, potentially offering a less invasive screening option in the future.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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350 people
The number who actually took part.
- Started
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Dec 2022
- Finished
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Sep 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient aged 50 years or older referred for screening colonoscopy after a positive FIT test or for endoscopic resection of a previously identified suspicious colorectal lesion Exclusion Criteria: * Very high risk of colorectal cancer: Lynch syndrome, Familial adenomatous polyposis, Peutz-Jeghers syndrome, Familial polyposis associated with a MutYH gene defect * Other solid cancers or haematological malignancies that are progressive and/or undergoing treatment (apart from basal cell skin carcinoma) * Contraindication to total colonoscopy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Caen University Hospital
Caen, France
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Clinique du Cèdre
Bois-Guillaume, France
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Dijon University Hospital
Dijon, France
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Other studies related to the condition(s) this trial covers.
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