Can three routine blood ratios predict who survives AML?
NCT ID NCT07810829
First seen Sep 09, 2026 · Last updated Sep 10, 2026 · Updated 1 time
Summary
Researchers at Assiut University Hospitals are studying whether three blood measures predict survival in adults newly diagnosed with non-M3 acute myeloid leukemia. The measures are the ratio of C-reactive protein to albumin, the ratio of albumin to fibrinogen, and the level of ferritin, a protein that stores iron. The study follows 208 patients aged 18 to 65 and tracks overall survival and complete remission after induction chemotherapy. The goal is to see whether these markers, which reflect inflammation and nutrition, can help doctors estimate a patient's outlook.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If these markers predict outcomes, doctors could use routine blood tests to sort patients by risk and tailor treatment earlier.
- What could go wrong
- This is an observational study, so it cannot prove that the markers cause outcomes or that acting on them helps. Results from one hospital may not apply elsewhere.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 208 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Sep 2026
An estimate. Start dates often move.
- Expected to finish
-
Sep 2028
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Newly diagnosed de novo non-M3 acute myeloid leukemia patients admitted to the Internal Medicine Department at Assiut University Hospitals.
- Ages
-
18 to 65 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 to 65 years * Newly diagnosed de novo non-M3 acute myeloid leukemia * Both sexes * Willingness to provide informed consent Exclusion Criteria: * \- Patient refusal * Significant cardiac, hepatic, or renal disease * Diabetes mellitus with polyneuropathy * Severe organ dysfunction (modified Marshall score ≥ 2) * History of MDS transformed to AML * Previous blood transfusions * Relapsed AML * Previous exposure to chemotherapy or radiotherapy
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Acute myeloid leukemia are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can an HDAC inhibitor wipe out residual leukemia cells?
- Can an experimental pill block a cancer-driving enzyme in hard-to-treat leukemia?
- Two-Drug combo targets leukemia that outsmarted its first treatment
- Tweaking donor cells may shield older transplant patients from a dangerous complication
- Can a drug and donor cells stop leukemia from returning after transplant?
- New drug combination targets Hard-to-Treat blood cancers