Could a blood flow 'Tourniquet' workout repair diabetic nerve damage?
NCT ID NCT07763795
First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time
Summary
This trial tests whether blood flow restriction (BFR) training—exercising with a cuff that partially limits blood flow—can improve blood sugar control, nerve function, pain, and quality of life in people with type 2 diabetes and peripheral neuropathy. Participants will be randomly assigned to either BFR with low-resistance exercises or the same exercises without BFR. The study aims to see if this innovative training method can help manage a common and debilitating complication of diabetes.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Blood flow restriction (BFR) training combined with low-resistance, high-repetition exercises
- What this could lead to
- If effective, this approach could offer a new, drug-free way to improve blood sugar control, nerve function, and quality of life for people with diabetic neuropathy.
- What could go wrong
- This is a small, early-stage trial, and results may not apply to everyone. The training involves restricting blood flow, which carries risks like blood clots or injury, especially in people with diabetes.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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60 people
The number who actually took part.
- Started
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Apr 2025
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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45 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * type 2 diabetes (≥5 years) patients diagnosed * random blood glucose ≥ 11.1mmol/L; * fasting blood glucose ≥ 7.0 mmol/L * Haemoglobin A1c 6.5%-9.5%. 2) Can walk independently, no severe joint limitations * Can safely perform resistance training * Stable diabetic \& neuropathy meds for 3+ months Exclusion Criteria: * suffers frequent hypoglycaemia, * severe diabetes complications * Diagnosed cases of neuromuscular disorders * history of stroke/DVT
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Sahiwal Diabetes and Foor care Clinic
Sahiwal, Punjab Province, Pakistan
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