Could gentle exercise with blood flow restriction help lung disease patients?
NCT ID NCT07315425
First seen Jun 24, 2026 · Last updated Aug 05, 2026 · Updated 3 times
Summary
This study tests whether low-intensity aerobic exercise with blood flow restriction (BFR) is safe and effective for people with interstitial lung disease (ILD). BFR uses a cuff to partially block blood flow, which may help build muscle with less strain. Thirty participants will try both regular low-intensity exercise and BFR exercise, with researchers measuring heart rate, blood pressure, oxygen levels, and muscle oxygen during and after each session.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Blood flow restriction (BFR) low-intensity aerobic exercise training
- What this could lead to
- If successful, this could point toward a safer way for people with ILD to build muscle and improve exercise capacity without overstressing their heart and lungs.
- What could go wrong
- This is a very early, small study (30 participants) looking only at immediate effects, not long-term benefits. The approach may not work or could cause discomfort or injury.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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30 people
The number who actually took part.
- Started
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Aug 2026
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosis of interstitial lung disease according to the European Respiratory Society (ERS) and American Thoracic Society (ATS) diagnostic criteria. * Willingness to participate in the study and provide written informed consent. Exclusion Criteria: * Presence of any acute infection at the time of the study. * Orthopedic or neurological conditions that may affect exercise capacity. * Contraindications to exercise testing according to the American College of Sports Medicine (ACSM) guidelines. * History of COVID-19 infection within the last three months. * Receiving treatments outside standard medical therapy. * Presence of peripheral arterial disease. * Presence of peripheral neuropathy. * Resting blood pressure greater than 160/100 mmHg. * History of deep vein thrombosis, pulmonary embolism, or stroke.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Gazi University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Cardiopulmonary Rehabilitation Unit
Ankara, Çankaya, 06490, Turkey (Türkiye)
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