New laser technique may improve bladder cancer surgery outcomes
NCT ID NCT07534631
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compared two surgical techniques for removing early-stage bladder tumors: a new laser method (holmium laser en-bloc resection) and the standard approach (conventional transurethral resection). 100 adults with suspected non-muscle-invasive bladder cancer were randomly assigned to one of the two procedures. The goal was to see which method provides better quality tumor samples and fewer side effects like bleeding or bladder perforation.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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100 people
The number who actually took part.
- Started
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Jan 2025
- Finished
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Jan 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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30 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 30 years or older. * Patients with cystoscopically suspected primary NMIBC planned for endoscopic resection. * Fit for surgery and anesthesia. * Able and willing to provide written informed consent and comply with follow-up. Exclusion Criteria: * Muscle-invasive disease suspected preoperatively or evidence of metastatic disease. * Prior bladder radiotherapy. * Severe comorbidity precluding surgery. * Pregnancy. * Inability to provide informed consent. * Upper urinary tract urothelial carcinoma or life expectancy less than 1 year
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Beni-Suef University Hospital
Banī Suwayf, Beni Suef Governorate, 62511, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Radiation instead of bladder removal: a new option for Hard-to-Treat bladder cancer?
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- Can a bladder rinse before surgery keep bladder cancer at bay?
- Timing chemotherapy around bladder surgery may cut recurrence