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Berry good news? blackcurrants tested for bone health in new trial

NCT ID NCT07365514

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 2 times

Summary

This early-stage trial is testing whether taking blackcurrant extract capsules can slow bone loss in women who have gone through menopause. The study will measure changes in bone density and gut bacteria over 12 months in 159 women aged 45-70. The goal is to see if the berries work through the gut-bone connection.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
blackcurrant extract
What this could lead to
If it works, this could point toward a simple dietary supplement to help maintain bone density after menopause.
What could go wrong
This is a very early phase 1 trial, so it may not show a clear benefit. The effect, if any, is likely to be modest and not a replacement for proven treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1

The first testing in people. Mainly checks safety and dose, usually in a small group.

Participants

About 159 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Sep 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

45 to 70 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * postmenopausal (defined as no more than 10 years since final menstrual cycle) females aged 45-70 years * not on hormone replacement therapy for at least one year before initiation of the study * maintaining normal exercise level (\< 7 hours/week) and willing to avoid exercise for 24 hours prior to blood and stool sampling * willing to ingest a dietary blackcurrant supplement or placebo (up to 1,176 mg/day, three 392mg capsules) * willing to avoid other dietary supplements for the duration of the study * willing to avoid intake of foods extremely rich in anthocyanins and fermented dairy products containing viable Bifidobacteria or Lactobacilli * willing to have three blood draws, three stool collections, and three bone scans Exclusion Criteria: * history of cardiovascular disease, osteoporosis, metabolic bone disease, cancer, diabetes mellitus, arthritis, or other chronic inflammatory diseases * current smokers * taking prescription medications known to alter bone and calcium metabolism * taking anabolic agents such as parathyroid hormone or growth hormone, or steroid within 3 months before the start of the study * taking medications that alter bleeding (such as antiplatelets or anticoagulants) or those with a bleeding disorder * alcohol consumption exceeding 2 drinks/day (approximately 14g of ethanol per drink) or a total of 12/week * those with planned surgery during the study period or within 2 weeks of ending the intervention * those with sensitivities or allergies to any of the ingredients for the placebo (rice powder) * planning a procedure that includes iodine, barium or nuclear medicine isotopes within the study period * UConn students and/or employees who any key personnel teach or who report to any key personnel * study key personnel, partners of key personnel, or dependents/relatives of any key personnel

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Connecticut, Department of Nutritional Sciences

    RECRUITING

    Storrs, Connecticut, 06269, United States

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