Berry good news? blackcurrants tested for bone health in new trial
NCT ID NCT07365514
First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 2 times
Summary
This early-stage trial is testing whether taking blackcurrant extract capsules can slow bone loss in women who have gone through menopause. The study will measure changes in bone density and gut bacteria over 12 months in 159 women aged 45-70. The goal is to see if the berries work through the gut-bone connection.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- blackcurrant extract
- What this could lead to
- If it works, this could point toward a simple dietary supplement to help maintain bone density after menopause.
- What could go wrong
- This is a very early phase 1 trial, so it may not show a clear benefit. The effect, if any, is likely to be modest and not a replacement for proven treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
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About 159 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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45 to 70 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * postmenopausal (defined as no more than 10 years since final menstrual cycle) females aged 45-70 years * not on hormone replacement therapy for at least one year before initiation of the study * maintaining normal exercise level (\< 7 hours/week) and willing to avoid exercise for 24 hours prior to blood and stool sampling * willing to ingest a dietary blackcurrant supplement or placebo (up to 1,176 mg/day, three 392mg capsules) * willing to avoid other dietary supplements for the duration of the study * willing to avoid intake of foods extremely rich in anthocyanins and fermented dairy products containing viable Bifidobacteria or Lactobacilli * willing to have three blood draws, three stool collections, and three bone scans Exclusion Criteria: * history of cardiovascular disease, osteoporosis, metabolic bone disease, cancer, diabetes mellitus, arthritis, or other chronic inflammatory diseases * current smokers * taking prescription medications known to alter bone and calcium metabolism * taking anabolic agents such as parathyroid hormone or growth hormone, or steroid within 3 months before the start of the study * taking medications that alter bleeding (such as antiplatelets or anticoagulants) or those with a bleeding disorder * alcohol consumption exceeding 2 drinks/day (approximately 14g of ethanol per drink) or a total of 12/week * those with planned surgery during the study period or within 2 weeks of ending the intervention * those with sensitivities or allergies to any of the ingredients for the placebo (rice powder) * planning a procedure that includes iodine, barium or nuclear medicine isotopes within the study period * UConn students and/or employees who any key personnel teach or who report to any key personnel * study key personnel, partners of key personnel, or dependents/relatives of any key personnel
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Connecticut, Department of Nutritional Sciences
RECRUITINGStorrs, Connecticut, 06269, United States
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- Can Omega-3s keep menopausal minds sharp?