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What's the best way to save bone after a tooth pull? new study compares options

NCT ID NCT07394738

Knowledge-focused Sponsor: Inonu University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at different materials used to preserve the jawbone after a tooth is removed. Forty adults will receive either a dentin graft, dentin plus hyaluronic acid, an allograft, or no graft at all. After 4 months, a small bone sample is taken during implant placement to measure new bone growth and how well the graft material integrated.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria Adults aged 18 years or older Indicated for tooth extraction in the anterior or premolar region of the maxilla or mandible Planned socket preservation and subsequent dental implant placement at the extraction site Adequate bone volume permitting atraumatic extraction Good oral hygiene and periodontal status compatible with socket preservation Willing and able to attend scheduled follow-up visits and undergo biopsy collection prior to implant placement Able to provide written informed consent Exclusion Criteria Systemic conditions known to impair bone or soft tissue healing (e.g., uncontrolled diabetes, immunosuppression, osteoporosis) Current use of medications affecting bone metabolism (e.g., bisphosphonates, corticosteroids, anti-resorptives) Active periodontal or periapical infection at the extraction site History of head and neck radiotherapy Smoking or tobacco use within the past 6 months Pregnancy or breastfeeding Known allergy or contraindication to grafting procedures or study-related materials Inability or unwillingness to comply with follow-up visits or biopsy procedures

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alveolar ridge preservation Bone regeneration Dental implants Tooth extraction

Contacts and locations

Locations

  • Inonu University Faculty of Dentistry

    Malatya, Battalgazi-Malatya, 44280, Turkey (Türkiye)

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