Scientists hunt for genetic signs to personalize bile duct cancer therapy
NCT ID NCT06648057
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study enrolls 100 adults with advanced biliary tract cancer who are already scheduled to receive a combination of two drugs (lenvatinib and pembrolizumab). Researchers will collect blood and tumor samples to look for genetic markers that might predict who responds best to treatment. The goal is to understand why some patients benefit more than others, not to test a new treatment directly.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2024
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with Advenced Biliary Tract Cancer will be recruited at CHA Bundang Medical Center
- Ages
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20 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with histologically or cytologically confirmed advanced biliary tract cancer. * Patients scheduled to receive Lenvatinib + Pembrolizumab for the treatment of advanced biliary tract cancer. * ECOG performance status of 0-2. * Patients aged 20 years or older at the time of treatment initiation. * Patients who understand and consent to participate in this study, and agree to provide samples obtained during the examination process. Exclusion Criteria: * Patients who do not consent to participate in the study or withdraw their consent.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Bundang CHA Medical Center
RECRUITINGSeongnam-si, Gyeonggi-do, 13496, South Korea
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