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New combo therapy hopes to boost immune attack on Hard-to-Treat melanoma

NCT ID NCT06784648

First seen Nov 19, 2025 · Last updated May 22, 2026 · Updated 23 times

Summary

This study tests a new drug called BI-1607 combined with two existing immunotherapies (ipilimumab and pembrolizumab) for people with advanced melanoma that has spread or cannot be removed. The goal is to see if adding BI-1607 helps the immune system better destroy cancer cells. About 35 adults whose melanoma worsened after prior treatment will participate.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Charité - Universitatsmedizin Berlin

    Berlin, Germany

  • Hospital Universitario Vall d'Hebron

    Barcelona, Spain

  • Sarah Cannon Research Institute UK

    London, Greater London, W1G 6AD, United Kingdom

  • The Christie NHS Foundation Trust

    Manchester, M20 4BX, United Kingdom

  • University Hospital 12 de Octubre

    Madrid, Spain

  • University Hospital Essen

    Essen, Germany

  • University Hospital Heidelberg

    Heidelberg, Germany

  • University Medical Center Mannheim, Ruprecht-Karl University of Heidelberg and Clinical Cooperation Unit Dermato-Oncology(G300) German Cancer Research Center(DKFZ)

    Mannheim, Germany

  • Velindre Cancer Centre

    Cardiff, Wales, CF14 2TL, United Kingdom

Conditions

Explore the condition pages connected to this study.