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Can light training with blood flow restriction boost ACL recovery?
NCT ID NCT07043569
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether combining light strength training with blood flow restriction (BFR) can help people rebuild muscle and strength after anterior cruciate ligament (ACL) surgery. Thirty participants will do daily BFR training for about 25 minutes as part of their outpatient rehab. The goal is to see if this approach improves muscle regeneration and knee function better than standard rehab alone.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- blood flow restriction training combined with strength exercises
- What this could lead to
- If it works, this could offer a more effective rehab method for people recovering from ACL surgery, helping them regain muscle and strength faster.
- What could go wrong
- This is a small, early-stage trial with only 30 participants, so results may not apply to everyone. The training is demanding and may not suit all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * ACL reconstruction * Ability to take part in an outpatient rehabilitation Exclusion Criteria: * Sickle Cell anemia * iatrogenic changes in the vessels of the lower limbs (stents, bypasses) * inflammation of the lower extremities
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University Hospital Bonn
RECRUITINGBonn, North Rhine-Westphalia, 53127, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could hidden knee bacteria explain why ACL surgeries fail?
- Which fixation method best heals a reconstructed ACL?
- Bone scaffold may help ACL grafts heal stronger
- Why some knees freeze after ACL surgery: scientists probe muscle inhibition
- Inside the knee: new navigation tech could make ACL surgery more precise