New MRI technique aims to stop breathing and heartbeats from blurring scans
NCT ID NCT05261633
First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 1 time
Summary
This study tests a new type of MRI scan that tries to reduce blurring caused by breathing, heartbeats, and other movements in the abdomen. Researchers will compare the new method to standard scans in 80 healthy volunteers and patients with liver metastases. The goal is to see if the new approach produces clearer, more reliable images for detecting cancer and other diseases.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Diffusion-weighted magnetic resonance imaging (DW-MRI) device
- What this could lead to
- If successful, this could lead to clearer, more reliable abdominal MRI scans for detecting and monitoring cancers and organ fibrosis without radiation or contrast dyes.
- What could go wrong
- This is an early-stage imaging study with only 80 participants, so results may not apply to all patients or scanners. The new method may not significantly improve image quality in practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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17 people
The number who actually took part.
- Started
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Nov 2023
- Finished
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Jun 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Healthy volunteers and people with known liver metastases that are 18 years or older.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria for Healthy Volunteers: * 18 years of age or older Exclusion Criteria for Healthy Volunteers: * Patients with contraindication to MRI (e.g. pacemaker, contraindicated metallic implants, claustrophobia, etc) * Pregnant or trying to become pregnant (as determined by self-report during MRI safety screening) Inclusion Criteria for Patients: * 18 years of age or older * Patients with at least one of the following: * Radiologically visible solid tumor liver metastasis, with at least one metastatic liver lesion must be a minimum of 8 mm in longest diameter * Patients presenting for liver lesion biopsy Exclusion Criteria for Patients: * Patients with contraindication to MRI (e.g. pacemaker, contraindicated metallic implants, claustrophobia, etc) * Patients with known contraindication to GBCA such as severe kidney disease or previously documented GFR \< 30 ml/min/1.73 m2 * Patients requiring intravenous (IV) conscious sedation for imaging are not eligible; patients requiring mild, oral anxiolytics for the MRI will be allowed to participate as long as the following criteria are met: * The subject has their own prescription for the medication. * The informed consent process is conducted prior to the self-administration of this medication * They come to the research visit with a driver * Pregnant or trying to become pregnant (as determined by self-report during MRI safety screening) * Stent in bile ducts * Partial hepatectomy
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Wisconsin School of Medicine and Public Health
Madison, Wisconsin, 53792, United States