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Beetroot and vitamin c: a natural way to lower blood pressure?

NCT ID NCT07242066

Disease control Sponsor: University of Nottingham Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether taking beetroot juice (which is rich in nitrates) together with vitamin C could lower blood pressure and improve blood vessel health in overweight adults aged 50-75. Fifteen participants took either the combination, beetroot juice alone, or a placebo. The goal was to see if the combo works better than beetroot alone for people at higher risk of heart disease.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
beetroot juice and vitamin C
What this could lead to
If it works, this could point toward a simple dietary supplement to help control blood pressure in overweight people.
What could go wrong
This was a very small, early study with only 15 participants. The results may not apply to everyone, and the effects might be small or temporary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

15 people

The number who actually took part.

Started

Nov 2024

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participant is willing and able to give informed consent for participation in the study. * Participant is willing and able to comply with the requirements of the study protocol. * Non-smoking men and women. * Aged between 50-75 years. * Overweight and obese (BMI: over 25.0 kg/m2). Exclusion Criteria: * Having taken part in a research study in the last 3 months involving invasive procedures or an inconvenience allowance. * Vegetarian. * Smoking. * Resting systolic blood pressure greater than 160 mmHg; diastolic blood pressure greater than 100 mmHg. * Active cancer and any diagnosis of malignant cancer in the last 5 years. * Excessive alcohol intake (\>21 units per week). * Allergy or intolerance to the intervention food (Beetroot juice). * Diagnosis of chronic or acute metabolic and inflammatory conditions that may interfere with the study outcomes. * Major surgical operations. * Use of prescribed psychiatric drugs (antidepressants, sedatives, antipsychotics), diuretics, organic nitrates, statins and proton pump inhibitors. * Use of prescribed hormonal therapies (oestrogens, thyroxin, and progesterone), anti-hypertensive (Calcium++ channel blockers, beta-blockers, and angiotensin-converting-enzyme (ACE) inhibitors), only if the prescription had started, or the dose had been started/changed, in the previous three months. * Non-prescribed dietary supplements if not stopped at least for 2 weeks before starting the trial. * Use of the mouthwash during the study was not allowed as it interferes with the conversion of oral nitrate into nitrite.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Blood pressure

Contacts and locations

Locations

  • David Greenfield Human Physiology Lab, Queens Medical Centre

    Nottingham, Nottinghamshire, NG7 2UH, United Kingdom

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Other studies related to the condition(s) this trial covers.