Beetroot juice tested as blood pressure aid for pre-eclampsia
NCT ID NCT06387784
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether beetroot juice can quickly lower blood pressure in pregnant women with pre-eclampsia, a serious condition causing high blood pressure. Researchers will give beetroot juice or a placebo to 60 pregnant women and measure changes in blood pressure, blood markers, and fetal blood flow. The goal is to see if beetroot juice could be a helpful addition to standard care.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
1. Pre-eclampsia pregnat women Inclusion Criteria: * Pregnant women at or beyond the 20th week of gestation. * Hospitalized at Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto. * Diagnosed with early-onset pre-eclampsia confirmed by a medical professional. * Capacity to provide written informed consent for study participation. Exclusion Criteria: * Multiple pregnancies. * Uncontrolled arterial hypertension (Systolic Blood Pressure \> 160 mmHg or Diastolic Blood Pressure \> 100 mmHg). * Pregnant women with a body mass index \> 40 kg/m² * Severe gestational complications. * History of food allergy with hypersensitivity to beetroot. * Smokers. * Chronic alcohol consumption. * Medications such as non-steroidal anti-inflammatory drugs, nasal decongestants, users of proton pump inhibitors and H2 receptor antagonists or any other medication that interferes with stomach pH. * Diagnosis of renal or hepatic disease affecting nitrate metabolism. * Cardiac conditions such as moderate to severe congestive heart failure and coronary artery disease. * Pre-existing type 1 or type 2 diabetes. 2. Healthy Pregnant Women Inclusion Criteria: * Healthy pregnant women at or beyond the 20th week of gestation. * Absence of pre-eclampsia diagnosis or other obstetric complications. * Willingness and ability to remain admitted at the Clinical Research Unit for the - period required by the study. * Capacity to provide written informed consent for study participation. Exclusion Criteria: \- The same exclusion criteria from Pre-eclampsia group apply.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto - USP
Ribeirão Preto, São Paulo, Brazil
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Hospital das Clínicas de Ribeirão Preto
Ribeirão Preto, São Paulo, 35180074, Brazil
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Other studies related to the condition(s) this trial covers.
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