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Beetroot juice may shield heart from coffee and cold shock

NCT ID NCT06602921

Knowledge-focused Sponsor: Loughborough University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study tested whether drinking beetroot juice (rich in nitrate) could reduce the strain on the heart and blood vessels caused by caffeine and cold exposure. Twenty-four healthy adults took beetroot powder, caffeine, and a cold foot bath while researchers measured blood pressure and artery function. The goal was to see if a simple dietary supplement could help the cardiovascular system handle everyday stressors better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
beetroot juice (nitrate-rich)
What this could lead to
If it works, this could point toward a simple dietary supplement to protect the heart during everyday stressors like caffeine and cold.
What could go wrong
This is a small, early-stage study in healthy people, not patients. Results may not apply to those with heart conditions or be strong enough to change recommendations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

24 people

The number who actually took part.

Started

Dec 2023

Finished

Apr 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Blood pressure \< 130 mmHg systolic and \< 85 mmHg diastolic. BMI between 18.5 and 29.9 kg/m2. Females must be naturally menstruating (regular length cycle and menses) or using a form of combined hormonal contraception (for at least 6 months). Exclusion Criteria: * Existing cardiovascular or metabolic conditions. Experience any adverse reactions to experimental procedures or supplements. Allergies to supplements or breakfast items. Involved in any other studies. Blood pressure \> 130 mmHg systolic and \> 85 mmHg diastolic.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Caffeine Cold exposure Nitrate

Contacts and locations

Locations

  • Loughborough University

    Loughborough, LE11 3TU, United Kingdom

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