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Gene editing breakthrough targets rare lung and liver disease

NCT ID NCT06389877

First seen Mar 27, 2026 · Last updated May 25, 2026 · Updated 13 times

Summary

This study tests a new gene editing medicine called BEAM-302 in 106 adults with Alpha-1 antitrypsin deficiency, a genetic condition that can cause lung and liver damage. The goal is to see if the treatment is safe and can raise levels of a protective protein in the blood. Participants will receive one dose and be monitored for side effects and protein levels over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clinical Study Center

    RECRUITING

    Birmingham, Alabama, 35233, United States

  • Clinical Study Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Clinical Study Center

    RECRUITING

    Charleston, South Carolina, 29425, United States

  • Clinical Study Center

    RECRUITING

    Adelaide, Australia

  • Clinical Study Center

    RECRUITING

    Fitzroy, Australia

  • Clinical Study Center

    RECRUITING

    Dublin, Ireland

  • Clinical Study Center

    RECRUITING

    Leiden, Netherlands

  • Clinical Study Center

    RECRUITING

    Auckland, New Zealand

  • Clinical Study Center

    RECRUITING

    Hamilton, New Zealand

  • Clinical Study Center

    RECRUITING

    London, United Kingdom

  • Clinical Study Center

    RECRUITING

    Southampton, United Kingdom

Conditions

Explore the condition pages connected to this study.