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Spinal fluid clues may predict Post-Birth depression

NCT ID NCT06947278

Knowledge-focused Sponsor: The First People's Hospital of Lianyungang Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 200 women having planned C-sections to see if levels of a brain protein called BDNF in their spinal fluid and blood could predict postpartum depression. Researchers measured BDNF before surgery and checked for depression symptoms up to 42 days after birth. The goal was to find a way to identify at-risk mothers early, but this was an observational study, not a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

200 people

The number who actually took part.

Started

May 2025

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients undergoing elective cesarean section under combined lumbar-rigid anesthesia in the First People's Hospital of Lianyungang City

Ages

20 to 35 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Meet the indications for cesarean section and have no contraindications to neuraxial anesthesia; 2. 20 years old≤ age ≤ 35 years old; 3. 37≤ gestational age\< 42; 4. American Society of Anesthesiologists (ASA) grade II\~III; 5. singleton pregnancy; 6. Voluntarily participate in this study and sign the informed consent form. Exclusion Criteria: 1. Unable to understand the content of the questionnaire correctly; 2. a clear history of mental illness, depression, cognitive impairment and other diseases; 3. Patients who have been taking sedative, analgesic and psychotropic drugs for a long time; 4. Those who have recently used glucocorticoids or immunosuppressants; 5. Those who are allergic to or have contraindications to any of the drugs used in this study; 6. Serious pregnancy complications, such as preeclampsia, placental hyperplasia, etc.; 7. Participated in other clinical studies within the last 3 months.

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Conditions

The condition(s) this trial relates to.

postpartum depression

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postpartum depression (PPD)

Contacts and locations

Locations

  • The Affiliated Lianyungang Hospital of Xuzhou Medical University

    Lianyungang, Jiangsu, 222000, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.