Hospital study aims to slash surgical infections by 88%
NCT ID NCT04600973
First seen Jun 27, 2026 · Last updated Jul 09, 2026 · Updated 2 times
Summary
This study tests different methods to stop the spread of dangerous bacteria in operating rooms and reduce infections after surgery. About 6,000 people having hip, knee, or spine surgery will take part. The goal is to find the best way to keep patients safe from infections.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 6,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2021
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Site Inclusion and Exclusion Criteria. * 250 patients (125 case pairs) per site in the active phase (N=3,000) * 250 patients (125 case pairs) per site in the sustainability phase (N=3,000) * Total N=6,000 * orthopedic total joint and spine procedures Site Inclusion Criteria: * operating room conducting orthopedic total joint and spine * Surgeons performing orthopedic total joint or spine Site Exclusion Criteria: \- medical centers actively enrolling patients in a bacterial transmission or infection prevention trial Patient Inclusion Criteria: \- all elective patients undergoing orthopedic total joint and spine Exclusion Criteria: * no requirement for anesthesia and/or placement of a peripheral intravenous catheter * lack of incision or informed, written consent * an allergy to chlorhexidine * povidone iodine or isopropyl alcohol * ASA health classification status\>5
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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Trustees of Dartmouth College
Hanover, New Hampshire, 03755, United States
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