Barbed sutures may speed up kidney surgery, small trial suggests
NCT ID NCT06526559
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether barbed sutures (V-Loc) are safer and easier to use than standard polyglactin sutures (Vicryl) in minimally invasive kidney surgery for a blocked ureter. Forty adults aged 18 to 60 were randomly assigned to receive either barbed or standard sutures during robotic or laparoscopic pyeloplasty. The main goals were to compare how long the suturing took, complication rates, and post-surgery drain output.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- barbed suture (V-Loc) and non-barbed polyglactin suture (Vicryl)
- What this could lead to
- If barbed sutures prove easier and faster, they could become the preferred option for this type of kidney surgery, potentially shortening operation times.
- What could go wrong
- This is a small, completed Phase 3 trial with only 40 participants, so results may not apply to all patients. Barbed sutures might not show clear benefits or could have unexpected complications.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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40 people
The number who actually took part.
- Started
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Nov 2023
- Finished
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May 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 18 to 60 undergoing robotic or laparoscopic dismembered pyeloplasty * History of dietls' crisis (Fever, pain) in a pelviureteric junction obstructed kidney * Decrease in glomerular filtration rate in a pelviureteric junction obstructed kidney Exclusion Criteria: * Contraindications for laparoscopy or robotic surgery as pulmonary obstructive or restrictive disease, and poor cardiovascular fitness * Uncontrolled diabetes mellitus * Morbid obesity * History of multiple major abdominal surgeries
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cairo University Kasr AlAiny Hospitals Urology Department 17B
Cairo, Egypt