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New study aims to unlock secrets of back pain recovery

NCT ID NCT07003802

Knowledge-focused Sponsor: University of California, San Diego Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at why some people with chronic low back pain and disc injuries don't recover fully with exercise. Researchers will measure muscle activity, brain signals, and tissue changes in 152 participants, including those having surgery or starting physical therapy. The goal is to find better ways to personalize rehabilitation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to more personalized physical therapy for chronic back pain, helping people recover better.
What could go wrong
This is an observational study, not testing a treatment. It may not directly lead to new therapies, and results may not apply to all back pain patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 152 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2025

Expected to finish

May 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Surgical group: * Individuals diagnosed with chronic disc injury (symptoms \> 3 months), * Individuals planning to undergo a spinal surgery to address the diagnosis of chronic disc injury Physical Therapy Group- * Individuals diagnosed with chronic disc injury (symptoms \>3 months), * Individuals initiating an exercise-based physical therapy program to address the diagnosis of chronic disc injury Healthy Control group - * Individuals with no history of chronic back pain (interfering pain lasting \>3 months) within the past 3 years, * no significant spinal pathology beyond normal age-related degenerative changes Exclusion Criteria: * Surgery/Physical therapy groups-History of lumbar spine surgery * Diabetes * Neuromuscular diseases * Epilepsy or other seizure disorder -Healthy control group - * History of lumbar spine surgery * History of interfering pain lasting \>3 months * Diabetes * Neuromuscular diseases * Epilepsy or other seizure disorder

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Conditions

The condition(s) this trial relates to.

Intervertebral Disc Displacement Low Back Pain Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Disc herniation Low back pain and core muscle

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • UC San Diego

    La Jolla, California, 92093, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.