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Engineered immune cells take on childhood cancers that Won't quit

NCT ID NCT07358260

First seen Jan 24, 2026 · Last updated May 01, 2026 · Updated 8 times

Summary

This early-stage study tests a new treatment called B7-H3 CAR T cells in 40 children and young adults whose solid tumors have come back or stopped responding to standard care. The therapy uses the patient's own immune cells, modified to target a marker called B7-H3 found on many cancer cells. The main goals are to see if the cells can be made successfully and to find the safest dose.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dana Farber Cancer Institite

    Boston, Massachusetts, 02115, United States

Conditions

Explore the condition pages connected to this study.