New drug shows promise for speeding recovery in severe pancreatitis

NCT ID NCT04681066

Completed Symptom relief Sponsor: CalciMedica, Inc. Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 27 times

Summary

This study tested a drug called Auxora in 216 adults hospitalized with acute pancreatitis and a related body-wide inflammation (SIRS). Participants received either Auxora or a placebo daily for three days. The main goal was to see if Auxora helped patients tolerate solid food sooner, a key sign of recovery. The trial is complete, and results will show if Auxora can shorten hospital stays and reduce complications.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

CAMC Institute for Academic Medicine

Charleston, West Virginia, 25304, United States
Cedars Sinai

Los Angeles, California, 90048, United States
Harbor UCLA Medical Center

Torrance, California, 90502, United States
Henry Ford Health System

Detroit, Michigan, 48202, United States
Houston Methodist Hospital

Houston, Texas, 77030, United States
IGMU (India Gandhi Medical)

Shimla, India
Icahn School of Medicine at Mount Sinai

New York, New York, 10029, United States
JIPMER

Puducherry, India
John Peter Smith Hospital

Fort Worth, Texas, 76104, United States
LA County Hospital - USC

Los Angeles, California, 90033, United States
Lisie Hospital

Kochi, India
Long Beach Medical Center

Long Beach, California, 90806, United States
MDM Hospital

Jodhpur, India
MTES' Sanjeevan Hospital

Pune, India
Malla Reddy Narayana

Hyderabad, India
Methodist Hospital

Saint Louis Park, Minnesota, 55426, United States
Northshore University Hospital

Manhasset, New York, 11030, United States
Northwestern University Hospital

Chicago, Illinois, 60611, United States
Ohio State University

Columbus, Ohio, 43201, United States
PGIMER, Chandigarh

Chandigarh, India
Regional One Health

Memphis, Tennessee, 38106, United States
Regions Hospital

Saint Paul, Minnesota, 55101, United States
Robley Rex VA Medical Center

Louisville, Kentucky, 40206, United States
SPMC

Bīkaner, India
Sarasota Memorial Health Care System

Sarasota, Florida, 34239, United States
Seven Star Hospital

Nagpur, India
Shree Giriraj Multispeciality Hospital

Rajkot, India
St. Luke's Regional Medical Center

Boise, Idaho, 83712, United States
Tampa General Hospital

Tampa, Florida, 33606, United States
The Stamford Hospital

Stamford, Connecticut, 06902, United States
Torrance Memorial Medical Center

Torrance, California, 90505, United States
UT Health Houston

Houston, Texas, 77030, United States
University of California at Irvine Medical Center

Orange, California, 92868, United States
University of Maryland

Baltimore, Maryland, 21201, United States
University of Missouri School of Medicine

Columbia, Missouri, 65212, United States
University of Virginia

Charlottesville, Virginia, 22908, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States

Conditions

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ACUTE PANCREATITIS SYSTEMIC INFLAMMATORY RESPONSE SYNDROME SYSTEMIC INFLAMMATORY RESPONSE SYNDROME