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Body's own fat may offer new hope for chronic tendon pain

NCT ID NCT07748793

Disease control Sponsor: Weill Medical College of Cornell University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This trial tests whether a one-time injection of a person's own concentrated fat can reduce pain and improve function in adults with chronic tendinopathy—tendon pain lasting more than three months that hasn't improved with usual treatments. Participants undergo a same-day procedure where a small amount of abdominal fat is removed, concentrated, and injected into the painful tendon under ultrasound guidance. The study follows participants for 12 months, tracking pain, function, and ultrasound images to see if the treatment helps.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Micro-fragmented adipose tissue (MFAT) injection
What this could lead to
If effective, this one-time procedure could offer a lasting, non-surgical option for people with stubborn tendon pain that hasn't improved with standard treatments.
What could go wrong
This is a small, single-group study without a comparison group, so results may not be conclusive. The procedure carries typical risks of liposuction and injection, such as pain, swelling, or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Jul 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria 1. Age 18-80 years. 2. Tendinopathy at any tendon location (e.g., rotator cuff/supraspinatus, lateral epicondyle, gluteal/hip, Achilles, patellar). 3. Confirmed tendon pathology: pain at the tendon site for \> 3 months AND pathology confirmed on ultrasound. 4. Failure of conservative treatment (e.g., activity modification, physical therapy, NSAIDs, corticosteroid injection, and/or PRP) for at least 6 weeks. 5. Able to provide informed consent and complete questionnaires in English. Exclusion Criteria 1. Full-thickness tendon tear. 2. Prior surgery at the target tendon site. 3. Injection or other intervention at the target tendon site within the prior 6 months. 4. Pregnancy or breastfeeding. 5. Active local or systemic infection, bleeding diathesis or anticoagulation precluding the procedure, or other condition that in the investigator's judgment makes participation unsafe. 6. Moderate-to-high-grade arthritis in the adjacent joint.

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Conditions

The condition(s) this trial relates to.

disease of the tendon epicondylitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic tendinopathy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Department of Rehabilitation Medicine WCMC

    New York, New York, 10065, United States