Simple exercise program may shield breast cancer patients from nerve damage
NCT ID NCT04583124
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a program of therapeutic exercise and relaxation techniques (called ATENTO) could prevent nerve damage (neurotoxicity) in women newly diagnosed with breast cancer. 42 women were split into two groups: one started the program before cancer treatment, the other during treatment. Researchers measured quality of life and cognitive function to see which timing worked best.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- therapeutic exercise and vagal activation techniques
- What this could lead to
- If it works, this could point toward a simple, drug-free way to prevent nerve damage from cancer treatment, improving quality of life for breast cancer patients.
- What could go wrong
- This is a very small, early study with only 42 participants, so results may not apply to everyone. The intervention is not a treatment for cancer itself, only for side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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42 people
The number who actually took part.
- Started
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Sep 2021
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * To have 18 years or older * To have a breast cancer diagnosis (Stage I-III) * To be on waiting list for medical adjuvant treatment with risk of central and/or peripheral neurotoxicity. * To have signed the informed consent. * To have medical clearance for participation. Exclusion Criteria: * To have a previous history of cancer or any cancer treatment. * Pregnant patients. * To participate in another intervention that could influence on the outcomes. * To have a neurodegenerative disease that affects central or peripheral nervous system and could influence the results.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Granada
Granada, 18016, Spain
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