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New drug could slow kidney damage in IgA nephropathy patients

NCT ID NCT04716231

First seen Oct 31, 2025 · Last updated Jun 17, 2026 · Updated 33 times

Summary

This phase 3 study tests a drug called atacicept in 376 adults with IgA nephropathy, a kidney disease that can lead to kidney failure. The goal is to see if atacicept can reduce protein in the urine and slow the loss of kidney function compared to a placebo. Participants must have a kidney biopsy confirming the disease and meet specific kidney function and protein levels.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ORIGIN 3 Global Site Contact Information

    Brisbane, California, 94005, United States

Conditions

The condition(s) this trial relates to.

IgA glomerulonephritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.