New pill combo aims to keep childhood leukemia away after transplant
NCT ID NCT07012044
First seen Jan 28, 2026 · Last updated May 18, 2026 · Updated 22 times
Summary
This early-stage trial tests the safety and best dose of an oral drug (ASTX727) plus a growth factor (filgrastim) in children with high-risk acute myeloid leukemia (AML) who have already had a stem cell transplant. The goal is to see if this maintenance therapy can help prevent the leukemia from coming back. About 47 children and young adults up to age 21 will take part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Children's Hospital of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Saint Jude Children's Research Hospital
RECRUITINGMemphis, Tennessee, 38105, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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