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New drug trial targets Hard-to-Treat cancers

NCT ID NCT05719558

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 21 times

Summary

This early-stage study tests a new drug called ASP1002 in adults with advanced solid tumors that have spread and have high levels of a protein called claudin 4. The main goals are to check the drug's safety, find the best dose, and see how well people tolerate it. Participants receive the drug through an IV infusion weekly, every two weeks, or every three weeks for up to two years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hartford HealthCare Cancer Institute at The Hospital of Central Connecticut

    RECRUITING

    Plainville, Connecticut, 06062, United States

  • HealthPartners Cancer Research Center

    RECRUITING

    Saint Paul, Minnesota, 55101, United States

  • Henry Ford Hospital

    RECRUITING

    Detroit, Michigan, 48202, United States

  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10029, United States

  • Mary Crowley Cancer Research Center

    RECRUITING

    Dallas, Texas, 75251, United States

  • NEXT Oncology Virginia

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • Norton Cancer Institute

    RECRUITING

    Louisville, Kentucky, 40202, United States

  • Prisma Health-Upstate Cancer Institute

    COMPLETED

    Greenville, South Carolina, 29605, United States

  • SCRI Oncology Partners

    COMPLETED

    Nashville, Tennessee, 37203, United States

  • Swedish Cancer Institute

    RECRUITING

    Edmonds, Washington, 21632, United States

  • University Hospitals of Cleveland

    RECRUITING

    Cleveland, Ohio, 44106, United States

  • University of Florida

    RECRUITING

    Gainesville, Florida, 32610, United States

  • University of Iowa Hospitals

    RECRUITING

    Iowa City, Iowa, 52242, United States

  • University of Texas Southwestern

    COMPLETED

    Dallas, Texas, 75235, United States

  • Yale University Cancer Center

    RECRUITING

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.